A key symptom in the early stages of Alzheimer's disease (AD) is the loss of declarative
memory. The anatomical substrate that supports this kind of memory involves the neural
circuits of the medial temporal lobe, and in particular, of the hippocampal formation and
adjacent cortex. A main feature of AD is the abnormal phosphorylation of the tau protein and
the presence of tangles. The sequence of cellular changes related to tau phosphorylation
and tangle formation has been studied with an antibody that binds to diffuse phosphotau …

Erratum: Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal
neurons in patients with Alzheimer's disease (Journal of Alzheimer's Disease (2011) 26: 3 (683-698)
DOI: 10.3233/JAD-2011-110659) | Documentos - Universidad Complutense de Madrid …
Erratum: Abnormal tau phosphorylation in the thorny excrescences of CA3 hippocampal
neurons in patients with Alzheimer's disease (Journal of Alzheimer's Disease (2011) 26: 3 (683-698)
DOI: 10.3233/JAD-2011-110659) …