Absence of CCR2 promotes proliferation of alveolar macrophages that control lung inflammation in acute respiratory distress syndrome in mice
VLS Oliveira, E Pollenus, N Berghmans… - International Journal of …, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) consists of uncontrolled inflammation that
causes hypoxemia and reduced lung compliance. Since it is a complex process, not all
details have been elucidated yet. In a well-controlled experimental murine model of
lipopolysaccharide (LPS)-induced ARDS, the activity and viability of macrophages and
neutrophils dictate the beginning and end phases of lung inflammation. CC chemokine
receptor type 2 (CCR2) is a critical chemokine receptor that mediates monocyte …
causes hypoxemia and reduced lung compliance. Since it is a complex process, not all
details have been elucidated yet. In a well-controlled experimental murine model of
lipopolysaccharide (LPS)-induced ARDS, the activity and viability of macrophages and
neutrophils dictate the beginning and end phases of lung inflammation. CC chemokine
receptor type 2 (CCR2) is a critical chemokine receptor that mediates monocyte …
[引用][C] Absence of CCR2 promotes proliferation of alveolar macrophages that can control lung inflammation in acute lung injury in mice
VL Soares de Oliveira, E Pollenus, N Berghmans… - … , Date: 2022/07/12-2022/07 …, 2022
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