Accelerated Development of Pharmaceuticals Past, Present, and Future

SR Byrn - Pharmaceutical Research, 2024 - Springer
… paper reviews the accelerated development of pharmaceuticals, … The work of Gardner and
Byrn in accelerated development … of PK/PD in accelerating pharmaceutical development. The …

Accelerated aging: prediction of chemical stability of pharmaceuticals

KC Waterman, RC Adami - International Journal of Pharmaceutics, 2005 - Elsevier
… Methods are discussed, with the appropriate caveats, for accelerated aging … pharmaceutical
ingredients. In particular, this review covers general thermal methods, as well as accelerated

[图书][B] Accelerated predictive stability (APS): fundamentals and pharmaceutical industry practices

F Qiu, G Scrivens - 2018 - books.google.com
… status of APS applications in the pharmaceutical industry. In addition, … pharmaceutical
company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical

Accelerating pharmaceutical process development with an acoustic droplet ejection-multiple reaction monitoring-mass spectrometry workflow

H Hu, AN Singh, D Lehnherr, V Mdluli… - Analytical …, 2024 - ACS Publications
… Herein, we introduce an ADE-multiple reaction monitoring-mass spectrometry (ADE-MRM-MS)
workflow to accelerate pharmaceutical process research and development (PR&D). This …

A scientific and statistical analysis of accelerated aging for pharmaceuticals. Part 1: accuracy of fitting methods

KC Waterman, JT Swanson, BL Lippold - Journal of Pharmaceutical …, 2014 - Elsevier
… applied to the use of accelerated processes for rapidly determining … While previous
examinations of accelerated stability modeling … Many of the calculations were carried out using the …

Data analytics on raw material properties to accelerate pharmaceutical drug development

A Benedetti, J Khoo, S Sharma, P Facco… - International Journal of …, 2019 - Elsevier
… of the boundaries, R e is the expected risk that relates to the true error, R emp is the empirical
risk … that the upper bound defined for R e holds)]. In particular, R emp relates to the error …

A Data-Driven Approach to Predicting Tablet Properties after Accelerated Test Using Raw Material Property Database and Machine Learning

Y Hayashi, Y Nakano, Y Marumo, S Kumada… - … and Pharmaceutical …, 2023 - jstage.jst.go.jp
accelerated test and to determine whether molecular descriptors affect tablet properties.
Tablets were prepared using 81 types of active pharmaceutical … two weeks of accelerated test. …

Accelerating Drug Discovery: Ai Powered Approaches in Pharmaceutical Research

S Chintala - 2024 4th International Conference on Innovative …, 2024 - ieeexplore.ieee.org
… creation of pharmaceuticals. Researchers now have the ability to manage massive amounts
of information, discover complex biomolecular interactions, and accelerate the development …

[HTML][HTML] ACCELERATE–Five years accelerating cancer drug development for children and adolescents

…, D Karres, G Reaman, R Rousseau… - European Journal of …, 2022 - Elsevier
… first framing ACCELERATE, this article highlights the achievements of ACCELERATE, a truly
… does not receive any funding from the pharmaceutical industry to support its work. Industry …

AI in Drug Discovery: Accelerating Pharmaceutical Research

M Kiani, F Nasir - … Journal of Advanced Engineering Technologies and …, 2024 - ijaeti.com
… Here, we paint a vision of the future landscape of pharmaceutical research, with AI at its core.
We discuss how AI is poised to accelerate drug discovery, make it more cost-effective, and …