Background Commercially available microbubbles such as Definity contain
octafluoropropane encapsulated in a lipid shell. This perfluorocarbon can be compressed
into liquid nanodroplets at room temperatures and activated with transthoracic diagnostic
ultrasound. The aim of this study was to determine the size range and acoustic
characteristics of Definity nanodroplets (DNDs) compared with Definity microbubbles
(DMBs). Methods An in vitro flow system was used with a diagnostic ultrasound transducer …