Activity-regulated cytoskeleton-associated protein predicts response to cognitive remediation among individuals with first-episode psychosis.
2017•psycnet.apa.org
Growing evidence suggests that cognitive remediation (CR)-defined by the Cognitive
Remediation ExpertsWorkshop as “a behavioral training based intervention that aims to
improve cognitive processes with the goal of durability and generalization”-mayameliorate
the cognitive deficits that accompany psychotic disorders. However, as a therapy, it is costly
and requires specially trained clinicians with expertise and instrumentation. Therefore, the
ability to pre-identify individuals who would most likely benefit from this intervention would …
Remediation ExpertsWorkshop as “a behavioral training based intervention that aims to
improve cognitive processes with the goal of durability and generalization”-mayameliorate
the cognitive deficits that accompany psychotic disorders. However, as a therapy, it is costly
and requires specially trained clinicians with expertise and instrumentation. Therefore, the
ability to pre-identify individuals who would most likely benefit from this intervention would …
Abstract
Growing evidence suggests that cognitive remediation (CR)-defined by the Cognitive Remediation ExpertsWorkshop as “a behavioral training based intervention that aims to improve cognitive processes with the goal of durability and generalization”-mayameliorate the cognitive deficits that accompany psychotic disorders. However, as a therapy, it is costly and requires specially trained clinicians with expertise and instrumentation. Therefore, the ability to pre-identify individuals who would most likely benefit from this intervention would decrease the time and cost of treatment. Consequently, several studies have investigated possible genetic predictors of response to CR. Focusing primarily on the dopaminergic modulator catechol-O-methyltransferase (COMT), results fromthese studies are equivocal andmay be confounded by the effects of antipsychotic medication.(PsycInfo Database Record (c) 2020 APA, all rights reserved)
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