Acute lymphocytic leukaemia presenting as a metabolic bone disease

SP Sukumar, K Balachandran, JP Sahoo… - Case …, 2013 - casereports.bmj.com
Case Reports, 2013casereports.bmj.com
A 7-year-old boy presented with the acute onset of low backache of 2 months duration. An x-
ray of thoracolumbar spine revealed multiple vertebral fractures, and biochemical evaluation
showed hypercalcaemia with a suppressed parathyroid hormone which raised the
possibilities of malignancy, granulomatous conditions or vitamin D toxicity. Despite the
absence of blast cells in his blood, the bone marrow biopsy was unequivocally diagnostic of
acute lymphoblastic leukaemia.
A 7-year-old boy presented with the acute onset of low backache of 2 months duration. An x-ray of thoracolumbar spine revealed multiple vertebral fractures, and biochemical evaluation showed hypercalcaemia with a suppressed parathyroid hormone which raised the possibilities of malignancy, granulomatous conditions or vitamin D toxicity. Despite the absence of blast cells in his blood, the bone marrow biopsy was unequivocally diagnostic of acute lymphoblastic leukaemia.
casereports.bmj.com
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