Acute nocturnal akathisia induced by clozapine
DISCUSSION Nocturnal akathisia may develop after acute neuroleptic treatment. Clozapine
mainly acts on D1, D3, and D4 receptors along with an antagonistic action on 5HT and α-1
adrenoceptors. 14 Although clozapine was being administered on a twice-daily dosage, the
delayed onset of akathisia, especially during the night only, occurred. This may have
resulted from a pharmacodynamic effect through serotonin-dopamine and α-receptor
interaction.
mainly acts on D1, D3, and D4 receptors along with an antagonistic action on 5HT and α-1
adrenoceptors. 14 Although clozapine was being administered on a twice-daily dosage, the
delayed onset of akathisia, especially during the night only, occurred. This may have
resulted from a pharmacodynamic effect through serotonin-dopamine and α-receptor
interaction.
[PDF][PDF] Acute Nocturnal Akathisia Induced By Clozapine
DPM Saddichha Sahoo, S Ameen - Ned Tijdschr Geneeskd, 2002 - academia.edu
DISCUSSION Nocturnal akathisia may develop after acute neuroleptic treatment. Clozapine
mainly acts on D1, D3, and D4 receptors along with an antagonistic action on 5HT and a-1
adrenoceptors. 14 Although clozapine was being administered on a twice-daily dosage, the
delayed onset of akathisia, especially during the night only, occurred. This may have
resulted from a pharmacodynamic effect through serotonin-dopamine and a-receptor
interaction.
mainly acts on D1, D3, and D4 receptors along with an antagonistic action on 5HT and a-1
adrenoceptors. 14 Although clozapine was being administered on a twice-daily dosage, the
delayed onset of akathisia, especially during the night only, occurred. This may have
resulted from a pharmacodynamic effect through serotonin-dopamine and a-receptor
interaction.
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