amounts of protein, minerals, vitamins, and fiber. However, P. aculeata is reported to contain
antinutrients and alkaloids in its leaves. In addition, in a study on growth and development,
Wistar rats fed with P. aculeata and casein as protein source grew less than the control
group (fed with casein only). Therefore, in this study, we evaluated, for the first time, the oral
acute toxicity of P. aculeata in rats and also the cytotoxicity behavior of the plant on lettuce …