Adsorption of human salivary mucins to hydroxyapatite

LA Tabak, MJ Levine, NK Jain, AR Bryan… - Archives of Oral …, 1985 - Elsevier
The interactions between low (MG2) and high (MG1) molecular-weight human
submandibular-sublingual mucin and hydroxyapatite (OHAp) were compared using a
quantitative assay. Data obtained appeared to empirically fit the Langmuir adsorption
isotherm. Apparent affinity constants derived from this isotherm indicated that MG1 had a
greater affinity for OHAp than did MG2. Inhibition studies revealed that salivary glycolipids
inhibited the interaction of MG1 and OHAp without influencing MG2 adsorption. In contrast …
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