Advancing 'real-world'trials that take account of social context and human volition

ABG Hansen, A Jones - Trials, 2017 - Springer
ABG Hansen, A Jones
Trials, 2017Springer
Background The recent paper in Trials by Porter and colleagues highlights the utility of
applying a critical realism approach in randomised trials, an approach central to the Medical
Research Council's (MRC) Framework for the Development and Evaluation of Complex
Healthcare Interventions. The MRC framework offers a pragmatic step towards a more open
systems approach that bridges randomised evaluation with social context and human
agency in an effort to improve the generalisability of trial outcomes. Main body The MRC …
Background
The recent paper in Trials by Porter and colleagues highlights the utility of applying a critical realism approach in randomised trials, an approach central to the Medical Research Council’s (MRC) Framework for the Development and Evaluation of Complex Healthcare Interventions. The MRC framework offers a pragmatic step towards a more open systems approach that bridges randomised evaluation with social context and human agency in an effort to improve the generalisability of trial outcomes.
Main body
The MRC framework has contributed to the proliferation of a more open systems approach in health research; however, the broader acceptance of the realist approach to health research does not seem to be emulated by norms in research fund allocation, which largely prioritises laboratory-based research.
Conclusion
This commentary is simply a plea, to those who make the strategic decisions regarding allocation of research funding, to support all phases of health intervention research in complex systems that contribute to the development of effective, translational and sustainable interventions in the promotion of health.
Springer
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