Adverse drug reactions–problems with spontaneous reporting systems: Festina Balidemaj

F Balidemaj - The European Journal of Public Health, 2017 - academic.oup.com
The European Journal of Public Health, 2017academic.oup.com
… Traditional methods of detecting ADEs in spontaneous reporting system databases rely on
manual case reviews by pharmacological/clinical experts. But due to increasing inconvenience
and large size of SRS databases, other methods were proposed consisting of quantitative and
automated approaches that are referred to as DMAs (data mining algorithms) or signal
detection algorithms. In the past few years, many other DMAs have been developed for
screening potential ADEs (Hauben et al, 2005). … Adverse drug reactions and adverse events …
Background Bone marrow transplant is a complex activity, the fourth per importance, preceded only by the transplants of liver/bowel, lung, pancreas and kidney and requires a huge investment of resources.
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