are incompletely understood. Methods Clinico-pathological risk factors for site of distant
metastasis and survival were analysed in patients with invasive breast cancer treated
between 1986 and 2006. Results Of 3553 patients, with median follow-up 6.32 years, 825
(23%) developed distant metastasis. The site of metastasis was bone in 196/825 (24%),
viscera in 540/825 (65%) and unknown in 89 (11%). Larger primary invasive tumour size …