Age-associated alteration of gene expression patterns in mouse oocytes
T Hamatani, G Falco, MG Carter… - Human molecular …, 2004 - academic.oup.com
Decreasing oocyte competence with maternal aging is a major factor in human infertility. To
investigate the age-dependent molecular changes in a mouse model, we compared the
expression profiles of metaphase II oocytes collected from 5-to 6-week-old mice with those
collected from 42-to 45-week-old mice using the NIA 22K 60-mer oligo microarray. Among
approximately 11 000 genes whose transcripts were detected in oocytes, about 5%(530)
showed statistically significant expression changes, excluding the possibility of global …
investigate the age-dependent molecular changes in a mouse model, we compared the
expression profiles of metaphase II oocytes collected from 5-to 6-week-old mice with those
collected from 42-to 45-week-old mice using the NIA 22K 60-mer oligo microarray. Among
approximately 11 000 genes whose transcripts were detected in oocytes, about 5%(530)
showed statistically significant expression changes, excluding the possibility of global …
[引用][C] AGE-ASSOCIATED ALTERATION OF GENE EXPRESSION PATTERNS IN MOUSE OOCYTES.
M DE FELICE - 2004 - iris.unina.it
AGE-ASSOCIATED ALTERATION OF GENE EXPRESSION PATTERNS IN MOUSE
OOCYTES. … AGE-ASSOCIATED ALTERATION OF GENE EXPRESSION PATTERNS IN
MOUSE OOCYTES / DE FELICE, Maurilio. - (2004). AGE-ASSOCIATED ALTERATION OF
GENE EXPRESSION PATTERNS IN MOUSE OOCYTES. …
OOCYTES. … AGE-ASSOCIATED ALTERATION OF GENE EXPRESSION PATTERNS IN
MOUSE OOCYTES / DE FELICE, Maurilio. - (2004). AGE-ASSOCIATED ALTERATION OF
GENE EXPRESSION PATTERNS IN MOUSE OOCYTES. …
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