Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors
NT Markov, CA Lindbergh… - Proceedings of the …, 2022 - National Acad Sciences
Aging is characterized by a progressive loss of brain volume at an estimated rate of 5% per
decade after age 40. While these morphometric changes, especially those affecting gray
matter and atrophy of the temporal lobe, are predictors of cognitive performance, the strong
association with aging obscures the potential parallel, but more specific role, of individual
subject physiology. Here, we studied a cohort of 554 human subjects who were monitored
using structural MRI scans and blood immune protein concentrations. Using machine …
decade after age 40. While these morphometric changes, especially those affecting gray
matter and atrophy of the temporal lobe, are predictors of cognitive performance, the strong
association with aging obscures the potential parallel, but more specific role, of individual
subject physiology. Here, we studied a cohort of 554 human subjects who were monitored
using structural MRI scans and blood immune protein concentrations. Using machine …
Age-related brain atrophy is not a homogenous process
NT Markov, CA Lindbergh, AM Staffaroni… - Proceedings of the …, 2022 - JSTOR
Aging is characterized by a progressive loss of brain volume at an estimated rate of 5% per
decade after age 40. While these morphometric changes, especially those affecting gray
matter and atrophy of the temporal lobe, are predictors of cognitive performance, the strong
association with aging obscures the potential parallel, but more specific role, of individual
subject physiology. Here, we studied a cohort of 554 human subjects who were monitored
using structural MRI scans and blood immune protein concentrations. Using machine …
decade after age 40. While these morphometric changes, especially those affecting gray
matter and atrophy of the temporal lobe, are predictors of cognitive performance, the strong
association with aging obscures the potential parallel, but more specific role, of individual
subject physiology. Here, we studied a cohort of 554 human subjects who were monitored
using structural MRI scans and blood immune protein concentrations. Using machine …
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