过去一年中添加的文章,按日期排序

Senescent glia link mitochondrial dysfunction and lipid accumulation

CN Byrns, AE Perlegos, KN Miller, Z Jin, FR Carranza… - Nature, 2024 - nature.com
35 天前 - biologic and molecular effect on the brain when we target senescent glia and extend
animal health, we bulk RNA-sequenced the brains of young (7 days) and aged (… targeting

Pediatric dilated cardiomyopathy: a review of current clinical approaches and pathogenesis

I Malinow, DC Fong, M Miyamoto, S Badran… - Frontiers in …, 2024 - frontiersin.org
35 天前 - Treatments for pediatric DCM aim to ameliorate symptoms… This review aims to
discuss the established biological … more effective age-specific therapeutic approaches to DCM. …

The HyperPed-COVID international registry: Impact of age of onset, disease presentation and geographical distribution on the final outcome of MIS-C

R Caorsi, A Consolaro, C Speziani, B Sozeri, K Ulu… - Journal of …, 2024 - Elsevier
37 天前 - … The aim of the study was to establish an international … rates exhibited a correlation
with the age and geographical areas. … access to biologic drugs and to intensive care facilities. …

Ergothioneine Protects Against UV-Induced Oxidative Stress Through the PI3K/AKT/Nrf2 Signaling Pathway

Y Li, J Gao, S Liu, S Chen, X Wei, Y Guan… - Clinical, Cosmetic …, 2024 - Taylor & Francis
37 天前 - … ) levels were measured with biological assay for evaluating … The markers of skin
aging and cell death were tested by … that blocks PI3K to confirm the target molecule of EGT. EGT …

Unraveling the Interplay Between FGF and NRF2 in Inflammatory Skin Diseases

M Koch - 2024 - research-collection.ethz.ch
37 天前 - … I found an age-dependent downregulation of Nrf2 activity … targets for future therapeutic
applications. In particular, we propose restricted activation of NRF2 as a possible therapy

AI-Enhanced RAIN Protocol: A Systematic Approach to Optimize Drug Combinations for Rectal Neoplasm Treatment

N Dashti, AA Kiaei, M Boush, B Gholami-Borujeni… - bioRxiv, 2024 - biorxiv.org
38 天前 - … timely and effective treatment to prevent severe health complications. • … targeted
drug therapies to combat tumor spread. … Given the intricacies of cancer biology, treatments often …

[PDF][PDF] Technical Evaluation and Standardization of the Human Thyroid

B Foley, K Hopperstad, J Gamble, SG Lynn… - Toxicological … - lnhlifesciences.org
40 天前 - … Of these, Tx-2 most closely simulated the biological state of the thyroid gland. …
human-relevant targets along multiple pathways (Figure 1). Finally, only donor age and BMI …

The TEOGIC study project: a comprehensive characterization of early onset gastrointestinal cancer in the Northern area of Spain

R Vera, N Castro, I Labiano, A Lecumberri, AE Huerta… - BMC cancer, 2024 - Springer
40 天前 - Biological samples prior to any onco-specific treatment will … Regarding the non-EOGIC
group, we set the lower age at 60 … Our overarching goal is to enhance the prognosis and …

OP0131 OCCURRENCE AND PREDICTORS OF MULTIPLE DMARD TREATMENT FAILURE IN RHEUMATID ARTHRITIS (RA): RESULTS FROM THE SWEDISH …

EB Wettersand, DDI Giuseppe, J Askling… - 2024 - ard.bmj.com
40 天前 - treatment switch of biological and targeted synthetic DMARDs (b/tsDMARDS) in
RA. … In the multivariable logistic regression model female gender, younger age, higher HAQ, …

P247 Pernicious anemia: epidemiological, clinical, biological profile and autoimmune associations–a Moroccan case series

C Hsain, M Kadiri, FZ Chabib, C Berhili, N Lagdali… - 2024 - gut.bmj.com
40 天前 - … This work aim to study the epidemiological, clinical, biological, and therapeutic
aspects … Median age 67 years, age ranged from 31 to 91 years. Eight patients did not need stent …