angiogenesis. However, to link the evidence for impaired angiogenesis to microvascular
dysfunction in aged tissues, we must compare adult vs. aged microvascular networks in
unstimulated scenarios. The objective of this study was to test the hypothesis that aged
microvascular networks are characterized by both fewer vessels and the impaired ability to
undergo angiogenesis. Mesentery tissues from adult (9-mo) and aged (24-mo) male Fischer …