Albino strains of Ophiostoma piliferum, Ophiostoma piceae and Ophiostoma floccosum used as single strain and in mixtures are tested for their abilities to increase the permeability of radiata pine sapwood after 2 and 4 weeks of incubation. The bio-treatments yielded permeability increments up to 1.9 and 2.4 times controls after 2 and 4 weeks, respectively. The fungus type involved in the treatments as well as the incubation time appeared as significant factors. Results also suggest that combinations of albino Ophiostoma spp. fungi could increase permeability to higher levels than individual ones, hinting at a possible synergistic relationship among them. Furthermore, treatments with a high concentration of O. floccosum seem particularly successful. Simultaneously to the increment of permeability such biotreatment might also offer protection against blue sap-stain. Further research is recommended to refine and find an optimum time of incubation, as well as the most effective combination and concentration of fungi.