The maintenance of mitochondrial function is closely linked to the control of senescence. In
our previous study, we uncovered a novel mechanism in which senescence amelioration in
normal aging cells is mediated by the recovered mitochondrial function upon Ataxia
telangiectasia mutated (ATM) inhibition. However, it remains elusive whether this
mechanism is also applicable to senescence amelioration in accelerated aging cells. In this
study, we examined the role of ATM inhibition on mitochondrial function in Hutchinson …