Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities of Novel Abietane Diterpenes from Salvia africana-lutea

NGER Etsassala, JA Badmus, TT Waryo, JL Marnewick… - Antioxidants, 2019 - mdpi.com
… the tested abietane diterpenes showed alpha amylase inhibitory activity, as … abietane
diterpenes and triterpenes with significant alpha glucosidase and alpha amylase inhibitory activities

Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities, Molecular Docking, and Antioxidant Capacities of Salvia aurita Constituents

NGER Etsassala, JA Badmus, JL Marnewick, EI Iwuoha… - Antioxidants, 2020 - mdpi.com
abietane diterpenes with strong alpha-glucosidase and alpha-amylase inhibitory activities
… and biological evaluation of alpha-glucosidase and alpha-amylase inhibitory activities of S. …

Glucose Uptake Activity and Cytotoxicity of Abietane Diterpenes and Triterpenes Isolated from Lamiaceae Plant Species

NGER Etsassala, KO Ndjoubi, TJ Mbira, B Pearce… - 2020 - preprints.org
… as potential candidates for novel plant-derived alternative … reported to be an effective inhibitor
of alpha-glucosidase [11], … alpha glucosidase and alpha amylase inhibitory activities [8]. …

An approach throughout in vitro studies on natural compounds as α-glucosidase inhibitors: A review

H Yuca - Studies in Natural Products Chemistry, 2024 - Elsevier
… various combinations of “alpha-glucosidase” alongside either “… vitro α-glucosidase inhibitory
activities of distinct molecules, … Among the tested abietane diterpenes, only clinopodiolide B …

In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes

J Riyaphan, DC Pham, MK Leong, CF Weng - Biomolecules, 2021 - mdpi.com
… (Rutaceae) showed strong inhibitory activity with an IC 50 of … to explore novel α-glucosidase
and α-amylase inhibitors … leaf extract on alpha-glucosidase activity in small intestine of …

New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects

H Kashtoh, KH Baek - Plants, 2023 - mdpi.com
Alpha-amylase is a metalloenzyme that facilitates digestion by … extract having higher enzymatic
inhibition activity (54.12–… Furthermore, abietane diterpenes, carnosol (Figure 6c) and 12-…

Recent updates on phytoconstituent alpha-glucosidase inhibitors: An approach towards the treatment of type two diabetes

H Kashtoh, KH Baek - Plants, 2022 - mdpi.com
… developing novel bioactive AGIs with strong inhibitory potential … α-glucosidase inhibition
activity and significantly improves … Two abietane-type diterpenoids, gauleucin E (Figure 5a) and …

A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
inhibition of alpha-amylase and alpha-glucosidase activity … review exhibiting alpha-glucosidase
inhibitory activity are already … were reported in the form of sesquiterpenoids, diterpenoids

Glucose-uptake activity and cytotoxicity of Diterpenes and Triterpenes isolated from Lamiaceae plant species

NGER Etsassala, KO Ndjoubi, TJ Mbira, B Pearce… - Molecules, 2020 - mdpi.com
… as potential candidates for novel plant-derived alternative … with potent alpha-glucosidase
and alpha-amylase inhibitory activities [8]. … Three abietane diterpenoids, such as 6β,7α-…

[PDF][PDF] Chemical isolation and electro-chemical characterization of antidiabetic compounds from selected South African lamiaceae plant species

NGER Etsassala - 2020 - uwcscholar.uwc.ac.za
… in general and more specifically abietane diterpene, which is … against alpha-glucosidase
showed strong inhibitory activities … in vitro alpha-amylase inhibitory activities among the tested …