Background: The aim of the present study was to map the pathophysiology of resting state
functional connectivity accompanying structural and functional abnormalities in children with
bipolar disorder. Methods: Children with bipolar disorder and demographically matched
healthy controls underwent resting-state functional magnetic resonance imaging. A model-
free independent component analysis was performed to identify intrinsically interconnected
networks. Results: We included 34 children with bipolar disorder and 40 controls in our …

… Brain blood flow and local synchrony abnormalities in medication-free patients with MDD …
HPA axis dysfunction in unmedicated major depressive disorder and its normalization by
pharmacotherapy correlates with alteration of neural activity in prefrontal cortex and limbic/paralimbic
regions. Psychiatry Res 2007;155:245-56. … Abnormal resting state corticolimbic blood
flow in depressed unmedicated patients with major depression: a (15)OH(2)O PET study.
Hum Brain Mapp 2012;33:272-9. …