Altered white matter connectivity in young people exposed to childhood abuse: a tract-based spatial statistics (TBSS) and tractography study

L Lim, H Hart, H Howells, MA Mehta, A Simmons… - Journal of Psychiatry and …, 2019 - jpn.ca
Background: Childhood abuse is associated with structural brain abnormalities. Few studies
have investigated white matter tract abnormalities in medication-naive, drug-free individuals
who experienced childhood abuse. We examined the association between childhood abuse
and abnormalities in white matter tracts in that population, controlling for psychiatric
comorbidities. Methods: We collected diffusion tensor imaging data for age-and sex-
matched youth with childhood abuse, psychiatric controls (matched for psychiatric …
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