Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type

ME Ahmed, MM Khan, H Javed, K Vaibhav… - Neurochemistry …, 2013 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in cognitive
decline and enhancement of oxidative loads in the brain. Flavonoids have been considered
to exert human health benefits by anti-oxidant and anti-inflammatory properties. The present
study is aimed to elucidate the neuroprotective effect of catechin hydrate (CH), a natural
flavanoid with potential antioxidant and anti-inflammatory properties, on
intracerebroventricular streptozotocin (ICV-STZ) induced neuronal loss and memory …
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