Amino acid sequence of a presynaptic neurotoxin from the venom of Notechis scutatus scutatus (Australian tiger snake).

J Halpert, D Eaker - Journal of Biological Chemistry, 1975 - ASBMB
The complete amino acid sequence of notexin, a presynaptic neurotoxin from the venom of
Notechis scutatus scutatus (Australian tiger snake), has been elucidated. The protein
consists of a single chain of 119 amino acids cross-linked by seven disulfide bridges and
has a formula weight of 13,578. The main fragmentation of the peptide chain was
accomplished with a staphylococcal protease specific for glutamoyl bonds. A cyanogen
bromide fragment and tryptic peptides were used to align the five major staphylococcal …
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