The Red Sea coastal zone is characterized by its sensitive, fragile, unique natural resources and habitats. In the Hurghada coastal region, major changes in the tourism industry have taken place in the last few decades. The detection of environmental changes, in a selected site of the Red Sea coastal zone, will be helpful to protect and develop this coastal environment. A methodology for separating natural and man-made changes in satellite images was developed. It was based on the following assumptions: (1) slow changes, which occur within the range of the class reflectance, represent a natural change rather than an anthropogenic one; (2) natural changes tend to be in the same land-use/land-cover class in each date, i.e. slow changes in the reflectance, not leading to changes in the type of land-use/land-cover class from the master image to the destination one; and (3) rapid changes in the reflectance of the Earth's objects are usually related to anthropogenic activities. This technique is used to identify and assess changes along the coast of Hurghada and Ras Abu Soma, the Red Sea. Results indicate serious human impacts and the necessity for control measures and monitoring. Recommendations are presented.