by employing Cupric nitrate/phosphate buffer/300 ohvdrogen peroxide system The present method afforded the biologically active and important hydroxy heterocycles. The hydroxylation takes place regioselectively without over oxidation.
Abstract
Nitrogen heterocycles have been efficiently hydroxvlated under mild and neutral conditions by employing Cupric nitrate/phosphate buffer/300 ohvdrogen peroxide system The present method afforded the biologically active and important hydroxy heterocycles. The hydroxylation takes place regioselectively without over oxidation.