An immune clock of human pregnancy

N Aghaeepour, EA Ganio, D Mcilwain, AS Tsai… - Science …, 2017 - science.org
… of pregnancy relies on finely tuned immune adaptations. We demonstrate that these adaptations
are precisely timed, reflecting an immune clock of pregnancy in … of all major immune cell …

Multiomic immune clockworks of pregnancy

LS Peterson, IA Stelzer, AS Tsai, MS Ghaemi… - Seminars in …, 2020 - Springer
immune clock of pregnancy and highlight recent technological advances that allow an integrated,
… assessment of immunological events involved in the natural chronology of pregnancy. …

A proteomic clock of human pregnancy

N Aghaeepour, B Lehallier, Q Baca, EA Ganio… - American journal of …, 2018 - Elsevier
… associated with enriched GO terms to immune features included in a recently published
predictive model of GA. This model, termed an immune clock of pregnancy, was derived from the …

A proposed model of a clock that governs the length of human pregnancy

T Rosen, B Wang - Reproduction, 2024 - rep.bioscientifica.com
… The mechanisms that govern the length of human pregnancy have not been determined, …
how the pregnancy clock may function to initiate human labor in uncomplicated pregnancies. In …

Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition

R Menon, EA Bonney, J Condon… - Human reproduction …, 2016 - academic.oup.com
… This review addresses the question of what mechanism controls the length of human
gestation and how its various related timing mechanisms are synchronized. Even with a term …

The regulations and role of circadian clock and melatonin in uterine receptivity and pregnancy—an immunological perspective

GCW Man, T Zhang, X Chen, J Wang… - American journal of …, 2017 - Wiley Online Library
… interaction between the circadian clock and melatonin within the immune system and their
… an immunological perspective, on the roles of circadian clock and melatonin in pregnancy. …

[HTML][HTML] A dynamic peripheral immune landscape during human pregnancy

X Liu, L Zhu, Z Huang, Z Li, R Duan, H Li, L Xie… - Fundamental …, 2022 - Elsevier
immune system during pregnancy and across pregnancy … an immune cell atlas of peripheral
blood from 27 pregnantpregnancy stages, including six in early-stage pregnancy (ES, …

Ageing in human parturition: impetus of the gestation clock in the decidua

JC Wijaya, R Khanabdali, HM Georgiou… - Biology of …, 2020 - academic.oup.com
… The endocrine clock refers to the … The immune clock is based on the chronology of immune
cell behaviors in peripheral blood, their interconnected pathways and changes as pregnancy

The immunity clock

I Martínez de Toda, C Vida… - The Journals of …, 2021 - academic.oup.com
… To answer this question, the immune functions that the Immunity Clock takes into account
were investigated in a group of women with diagnosed anxiety (N = 10) as well as in a group of …

Single-cell profiling of the peripheral blood immune landscape during mid-and late-stage pregnancy

F Gao, X Li, H Wang, Z Xu, W Qian… - Physiological …, 2024 - journals.physiology.org
… in late-stage pregnancy. To conclude, we present detailed changes in the immune
response occurring in pregnant women from mid- to late-stage gestation, revealing significant …