An overview of ATP synthase, inhibitors, and their toxicity

AR Althaher, M Alwahsh - Heliyon, 2023 - cell.com
Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in
generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism
cannot be overstated, as malfunction of ATP synthase has been linked to various
pathological conditions. Both natural and synthetic ATP synthase inhibitors have been
extensively studied, revealing their inhibitory sites and modes of action. These findings have
opened exciting avenues for developing new therapeutics and discovering new pesticides …

An overview of ATP synthase, inhibitors, and their toxicity

AR Althaher, M Alwahsh - europepmc.org
Mitochondrial complex V (ATP synthase) is a remarkable molecular motor crucial in
generating ATP and sustaining mitochondrial function. Its importance in cellular metabolism
cannot be overstated, as malfunction of ATP synthase has been linked to various
pathological conditions. Both natural and synthetic ATP synthase inhibitors have been
extensively studied, revealing their inhibitory sites and modes of action. These findings have
opened exciting avenues for developing new therapeutics and discovering new pesticides …
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