Land Surface Temperature (LST) is an important climatic factor in both ecological and climate studies. LST is the temperature recorded at the interface between the earth surface and the immediate atmosphere. The need to predict and manage the potential impact of climate change due to increased surface temperature necessitates an accurate study on micro level. This paper was aimed at demonstrating the potential use of satellite Remote Sensing (RS) and Geographical Information System (GIS) for monitoring changes in Land surface temperature and vegetation over Akure city in Ondo state, Nigeria. The study employed the spatial modeler tool of the ERDAS IMAGINE 9.2 software in estimating Land Surface Temperature (LST) acquired from Landsat TM and ETM+ satellite imageries for January 1991 and 2011 and also, air temperature data from Nigeria meteorological agency from 1986-2011. Result shows that the mean annual air temperature was 26.71OC for the period of 25years while the January land surface temperature was 25.46OC in 1991 and 28.85OC in 2011, indicating a 3.4OC rise in January surface temperature. Also, observed was the significant shift in the landuse and landcover over the study area resulting to a reduction in forest and vegetation cover from 89% in 1991 to 23% in 2011, while built-up areas recorded a massive increment from 7% to 74%. However, the built-up lands indicate an expansion of urbanization away from the city center towards the outskirts.