Analysis of expression patterns of IGF-1, caspase-3 and HSP-70 in developing human tooth germs

D Kero, DK Govorko, IM Mikic, K Vukojevic, L Cigic… - Archives of oral …, 2015 - Elsevier
Aims To analyze expression patterns of IGF-1, caspase-3 and HSP-70 in human incisor and
canine tooth germs during the late bud, cap and bell stages of odontogenesis. Materials and
methods Head areas or parts of jaw containing teeth from 10 human fetuses aged between
9th and 20th developmental weeks were immunohistochemically analyzed using IGF-1,
active caspase-3 and HSP-70 markers. Semi-quantitative analysis of each marker's
expression pattern was also performed. Results During the analyzed period, IGF-1 and HSP …
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