Anti-aggressive activity of methyl jasmonate and the probable mechanism of its action in mice

S Umukoro, AT Eduviere, AC Aladeokin - Pharmacology Biochemistry and …, 2012 - Elsevier
This study examines the anti-aggressive activity of methyl jasmonate (MJ) and its probable
mechanism of action in mice. Male mice that showed aggression after housing individually
with female counterparts for 3weeks or kept in isolation for 4weeks were treated with MJ,
vehicle or haloperidol (HP) 60min before the test for aggression. Effects of p-
chlorophenylalanine (PCPA) or fluoxetine (FL) given alone or in combination with MJ were
also investigated. In the interaction studies, PCPA or FL was given to the animals 30min …
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