Anti-malarial activity of N6-substituted adenosine derivatives. Part I

A Golisade, J Wiesner, C Herforth, H Jomaa… - Bioorganic & medicinal …, 2002 - Elsevier
… is resistant to most commonly used anti-malarial drugs. When the resistance pattern …
derivatives obtained by our group posess improved anti-malarial activity and will be reported as Part

Antimalarial activity of N6-substituted adenosine derivatives. Part 3

C Herforth, J Wiesner, P Heidler, S Sanderbrand… - Bioorganic & medicinal …, 2004 - Elsevier
… for anti-malarial activity versus the Dd2 strain of Plasmodium falciparum. Further, this series
and 62 adenosine derivativesadenosine derivatives displayed moderate but significant …

Antimalarial Activity of N6-Substituted Adenosine Derivatives (Part 2)

C Herforth, J Wiesner, S Franke… - Journal of …, 2002 - ACS Publications
adenosine derivatives discussed in part 1 of this investigation, the novel series of N 6 ,5‘-disubstituted
adenosine analogues displays significant activityadenosine derivatives will be …

Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5-amino-5-deoxyadenosines

V Zohrabi-Kalantari, P Heidler, M Kaiser, R Brun… - Molecular …, 2010 - Springer
adenosine derivatives might be useful tools for the further biochemical exploration of the role
and function of adenosine binding proteins in adenosine … of N6-substituted adenosine 5, 6 …

Cytokinin nucleosides-natural compounds with a unique spectrum of biological activities

M S. Drenichev, V E. Oslovsky… - Current topics in …, 2016 - benthamdirect.com
… to adenosine receptors may underlie at least in a part of … 1-N-Alkylation of adenosine followed
by the Dimroth re… used for the preparation of N6-substituted adenosine derivatives [93]. It …

Synthesis and Antimalarial Activity of Novel N 6-Substituted Adenosine Derivatives

PH Heidler, C Herforth, A Link - Nucleosides, Nucleotides and …, 2003 - Taylor & Francis
… Substituted adenosine analogues were previously obtained as hits in a screening program
… in vitro antimalarial activity of a new series of adenosine derivatives 5 combining available …

Current trends in antimalarial chemotherapy

A Kumar, SB Katiyar, A Agarwal, PMS Chauhan - Drugs Fut, 2003 - access.portico.org
… Compound 43 was found to exhibit potent antimalarial activity with an IC50 value of 12 µM
(… of N6-substituted adenosine derivatives, compound 71 showed potent antimalarial activity in …

Bioactive carbohydrates and recently discovered analogues as chemotherapeutics

TM Wrodnigg, FK Sprenger - Mini Reviews in Medicinal …, 2004 - benthamdirect.com
adenosine derivatives are therefore prone to selective uptake by the parasite. N6-Substituted
adenosine derivatives … , were synthesised and their anti malarial activity tested [14] and …

Schiff bases: multipurpose pharmacophores with extensive biological applications

KS Munawar, SM Haroon, SA Hussain… - Journal of Basic & …, 2018 - set-publisher.com
… This paper focus on the biological activities of Schiff bases of various types and hence
makes them important precursors in designing drugs for medical treatment. The biological …

Oximes of nucleosides and related compounds: Synthesis, reactions and biological activity

E Abele, R Abele - Current Organic Synthesis, 2018 - benthamdirect.com
Adenosine-5-oxime derivatives were used in the treatment of … In vitro antimalarial activity
of N6-modified purine analogs. … Synthesis and biological activity of novel N6substituted and 2…