Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

TF Gajewski, FW Fitch - Journal of immunology (Baltimore, Md …, 1988 - journals.aai.org
… Our results suggest that Thl cells can inhibit the proliferation of Th2 cells via the action of
IFN-y, without affecting lymphokine production, as measured by IL-4 secretion, by these cells. …

Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or …

TF Gajewski, E Goldwasser, FW Fitch - Journal of immunology …, 1988 - journals.aai.org
inhibit hemopoietic colony formation (28). In this report, we demonstrate that rIFN-y inhibits
the proliferationinhibited following stimulation with rIL-3 or rGM-CSF. rIFN-y is also shown to …

Anti-proliferative effect of IFN-gamma in immune regulation. IV. Murine CTL clones produce IL-3 and GM-CSF, the activity of which is masked by the inhibitory action of …

TF Gajewski, FW Fitch - Journal of immunology (Baltimore, Md …, 1990 - journals.aai.org
proliferation of new leukocytes to assist in defense, the release of IL-3 and GM-CSF during
the course of an immune … Recently, we have reported that IFN--/ inhibits proliferation of murine …

The synergistic anti-proliferative effect of gamma-interferon and human lymphotoxin.

SH Lee, BB Aggarwal, E Rinderknecht… - … (Baltimore, Md.: 1950 …, 1984 - journals.aai.org
… in the Go/GI phase of the cell cycIe, concomitant with the observation that the proliferation of
the cells is strongly inhibited. The physiologic implication of these observations is discussed. …

Interferon-gamma (IFN-γ): Exploring its implications in infectious diseases

G Kak, M Raza, BK Tiwari - Biomolecular concepts, 2018 - degruyter.com
… by IFN-γ activity via induction of an anti-proliferative state. … successfully limit Hepatitis C virus
proliferation in HIV+ (Human … immune protective responses exerted by IFN-γ are inhibited by …

[HTML][HTML] Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or …

H Ding, G Wang, Z Yu, H Sun, L Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
immune regulation, leukocyte transportation, cell proliferation, … inhibit IFNγR expression from
escaping antiviral immune … to become insensitive to the anti-proliferative effects of the IFN-γ/…

Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma.

WY Almawi, ML Lipman, AC Stevens… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
proliferation assay of human peripheral blood mononuclear leukocytes, we show that
GCS-mediated anti-proliferative effects … GCS inhibit mitogen-driven and alloantigen-induced T cell …

Structure and effects of interferon-gamma

GR Adolf - Oncology, 1985 - karger.com
… tion of Burkitt's lymphoma cells is inhibited by IFN-a in … of the antiviral and anti proliferative
activities. The majority of IFN-… Selective inhibitory effects of Hu-IFNgamma on the agarose …

… of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma …

TF Gajewski, J Joyce, FW Fitch - Journal of immunology (Baltimore …, 1989 - journals.aai.org
… -y inhibits the proliferation of TH2 but not TH1 HTL clones (3). If this antiproliferative effect of
IFN-y … tion of the newly derived TH2 clones should be inhibited by IFN-y. Figure 5 depicts the …

A direct role for IFN-gamma in regulation of Th1 cell development.

LM Bradley, DK Dalton, M Croft - Journal of immunology (Baltimore …, 1996 - journals.aai.org
… -IFN-y largely inhibited the development of effectors producing … antiproliferative effects on
Th2 cells (48), a negative effect on … in immune regulation. Differential selection of Thl and Th2 …