viruses and fungi [1]; these microorganisms play the significant roles in health and can
cause oral diseases [2]. One of the most abundant bacteria of the oral microbiota is
Streptococcus mutans, which is recognised as the main causal agent of dental caries
because it can metabolise sugars, generate lactic acid, survive in a self-generated acidic
environment. It adheres and grow on smooth and hard surfaces, such as enamel, to …