detrimental effects in children. Antifibrinolytic agents are often used to reduce perioperative
blood loss. Clinical trials have evaluated their effect in children undergoing surgical
correction of scoliosis but no systematic review has been published. We performed a
systematic review on the efficacy and safety of antifibrinolytic drugs in children undergoing
scoliosis surgery. Objectives To assess the efficacy and safety of aprotinin, tranexamic acid …