Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children

A Tzortzopoulou, MS Cepeda… - … of systematic reviews, 2008 - cochranelibrary.com
Background Scoliosis surgery is often associated with substantial blood loss and potential
detrimental effects in children. Antifibrinolytic agents are often used to reduce perioperative
blood loss. Clinical trials have evaluated their effect in children undergoing surgical
correction of scoliosis but no systematic review has been published. We performed a
systematic review on the efficacy and safety of antifibrinolytic drugs in children undergoing
scoliosis surgery. Objectives To assess the efficacy and safety of aprotinin, tranexamic acid …

Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children

ED McNicol, A Tzortzopoulou… - Cochrane Database …, 2016 - cochranelibrary.com
Background This is an updated version of the original Cochrane review first published in
2008. Scoliosis surgery is often associated with substantial blood loss and potentially
detrimental effects in children. Antifibrinolytic agents are often used to reduce perioperative
blood loss. Clinical trials have evaluated their efficacy in children undergoing surgical
correction of scoliosis, but no systematic review has been published. This review was first
published in 2008 and was updated in 2016. Objectives To assess the efficacy and safety of …
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