Antimicrobial activity and surface properties of an acrylic resin containing a biocide polymer

MA Compagnoni, AC Pero, SMM Ramos… - …, 2014 - Wiley Online Library
MA Compagnoni, AC Pero, SMM Ramos, J Marra, AG Paleari, LS Rodriguez
Gerodontology, 2014Wiley Online Library
Objective To evaluate the antimicrobial activity and surface properties of an acrylic resin
containing the biocide polymer poly (2‐tert‐butylaminoethyl) methacrylate (PTBAEMA).
Background Several approaches have been proposed to prevent oral infections, including
the incorporation of antimicrobial agents to acrylic resins. Materials and methods Specimens
of an acrylic resin (Lucitone 550) were divided into two groups: 0%(control) and 10%
PTBAEMA. Antimicrobial activity was assessed by adherence assay of one of the …
Objective
To evaluate the antimicrobial activity and surface properties of an acrylic resin containing the biocide polymer poly (2‐tert‐butylaminoethyl) methacrylate (PTBAEMA).
Background
Several approaches have been proposed to prevent oral infections, including the incorporation of antimicrobial agents to acrylic resins.
Materials and methods
Specimens of an acrylic resin (Lucitone 550) were divided into two groups: 0% (control) and 10% PTBAEMA. Antimicrobial activity was assessed by adherence assay of one of the microorganisms, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Surface topography was characterised by atomic force microscopy and wettability properties determined by contact angle measurements.
Results
Data of viable cells (log (CFU + 1)/ml) for S. aureus (control: 7.9 ± 0.8; 10%: 3.8 ± 3.3) and S. mutans (control: 7.5 ± 0.7; 10%: 5.1 ± 2.7) showed a significant decrease with 10% of PTBAEMA (Mann–Whitney, p < 0.05). For C. albicans (control: 6.6 ± 0.2; 10%: 6.6 ± 0.4), there was no significant difference between control and 10% of PTBAEMA (Kruskal–Wallis, p > 0.05). Incorporating 10% PTBAEMA increased surface roughness and decreased contact angles.
Conclusion
Incorporating 10% PTBAEMA into acrylic resins increases wettability and roughness of acrylic resin surface; and decreases the adhesion of S. mutans and S. aureus on acrylic surface, but did not exhibit antimicrobial effect against C. albicans.
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