Antioxidant activity of CAPE (caffeic acid phenethyl ester) in vitro can protect human sperm deoxyribonucleic acid from oxidative damage
Ş Ayla, G Tunalı, BE Bilgiç, K Sofuoğlu, AA Özdemir… - Acta histochemica, 2018 - Elsevier
Purpose Sperm processing (eg, centrifugation) used in preparation for assisted reproduction
can result in excessive generation of reactive oxygen species (ROS) and potential sperm
damage. The use of antioxidants during sperm processing has been shown to prevent
iatrogenic sperm damage, including DNA damage. In this study, we evaluated the effect of
caffeic acid phenethyl ester (CAPE) on oxidative stress mediated sperm dysfunction and
DNA damage. Methods Semen samples were obtained to liquefy at room temperature. After …
can result in excessive generation of reactive oxygen species (ROS) and potential sperm
damage. The use of antioxidants during sperm processing has been shown to prevent
iatrogenic sperm damage, including DNA damage. In this study, we evaluated the effect of
caffeic acid phenethyl ester (CAPE) on oxidative stress mediated sperm dysfunction and
DNA damage. Methods Semen samples were obtained to liquefy at room temperature. After …
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