Antioxidative hydrogel-embedded polyethersulfone membrane with improved hemocompatibility to alleviate oxidative stress

L Xu, H Ji, R Zhong, S Cheng, G Dang, T Xu… - Journal of Membrane …, 2023 - Elsevier
Oxidative stress (OS) is an important pathogenesis mechanism and a non-traditional risk
factor for mortality in patients with end-stage renal diseases. Due to the absence of
antioxidant function and poor hemocompatibility of current hemodialysis membranes, OS is
further aggravated during hemodialysis. In this work, Polyethersulfone membrane with
hydrogel-embedded structure is fabricated by combining one-pot in-situ cross-linking
polymerization and phase-separation, followed by grafting of tannic acid (TA). The obtained …

Antioxidative Hydrogel-Embedded Polyethersulfone Membranewith Improved Hemocompatibility to Alleviate Oxidative Stress

L Xu, H Ji, R Zhong, S Cheng, G Dang, T Xu… - Available at SSRN … - papers.ssrn.com
Oxidative stress (OS) is an important pathogenesis mechanism and a non-traditional risk
factor for mortality in patients with end-stage renal diseases. Due to the absence of
antioxidant function and poor hemocompatibility of current hemodialysis membranes, OS is
further aggravated during hemodialysis. In this work, Polyethersulfone membrane with
hydrogel-embedded structure is fabricated by combining one-pot in-situ cross-linking
polymerization and phase-separation, followed by grafting of tannic acid (TA). The obtained …
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