[PDF][PDF] Antiproliferative activity of aqueous extract of Piper betle L. and Psidium guajava L. on KB and HeLa cell lines
AR Fathilah, R Sujata, AW Norhanom… - J Med Plants …, 2010 - academicjournals.org
AR Fathilah, R Sujata, AW Norhanom, MI Adenan
J Med Plants Res, 2010•academicjournals.orgPiper betle plants on the proliferation of cancerous cell lines, that is, KB and HeLa cell line.
Using the neutral red cytotoxicity assay, the IC50 of P. guajava and P. betle were determined
at 29.0±0.4 and 29.5±0.3 µg/ml, respectively, indicating both plant extracts equally potent for
the treatment of cancerous oral epidermal lesions. However, a less potent anti-proliferative
activity was recorded by P. guajava towards HeLa cell line with an IC50 of 51.0±0.6 µg/ml,
whereas P. betle extract did not affect the proliferation of HeLa.
Using the neutral red cytotoxicity assay, the IC50 of P. guajava and P. betle were determined
at 29.0±0.4 and 29.5±0.3 µg/ml, respectively, indicating both plant extracts equally potent for
the treatment of cancerous oral epidermal lesions. However, a less potent anti-proliferative
activity was recorded by P. guajava towards HeLa cell line with an IC50 of 51.0±0.6 µg/ml,
whereas P. betle extract did not affect the proliferation of HeLa.
Piper betle plants on the proliferation of cancerous cell lines, that is, KB and HeLa cell line. Using the neutral red cytotoxicity assay, the IC50 of P. guajava and P. betle were determined at 29.0±0.4 and 29.5±0.3 µg/ml, respectively, indicating both plant extracts equally potent for the treatment of cancerous oral epidermal lesions. However, a less potent anti-proliferative activity was recorded by P. guajava towards HeLa cell line with an IC50 of 51.0±0.6 µg/ml, whereas P. betle extract did not affect the proliferation of HeLa.
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