Importance Antipsychotic medications are associated with increased mortality in older adults
with dementia, yet their absolute effect on risk relative to no treatment or an alternative
psychotropic is unclear. Objective To determine the absolute mortality risk increase and
number needed to harm (NNH)(ie, number of patients who receive treatment that would be
associated with 1 death) of antipsychotic, valproic acid and its derivatives, and
antidepressant use in patients with dementia relative to either no treatment or …