Apoptosis-inducing effect of a palladium (II) saccharinate complex of terpyridine on human breast cancer cells in vitro and in vivo

F Ari, B Cevatemre, EII Armutak, N Aztopal… - Bioorganic & Medicinal …, 2014 - Elsevier
… , the Pd(II) complex was found to exhibit anti-growth effects against breast cancer cell lines
(MCF-7 and MDA-MB-231) by inducing apoptosis in vitro. Moreover, the Pd(II) complex was …

Promising anti-growth effects of palladium (II) saccharinate complex of terpyridine by inducing apoptosis on transformed fibroblasts in vitro

MD Coskun, F Ari, AY Oral, M Sarimahmut… - Bioorganic & medicinal …, 2013 - Elsevier
apoptosis-inducing effects in cancer cells. For this purpose, a palladium(II)-saccharinate
complex containing terpyridine which … the human cervical epitheloid carcinoma, human chronic …

The role of cell cycle progression for the apoptosis of cancer cells induced by palladium (II)-saccharinate complexes of terpyridine

O Kacar, B Cevatemre, I Hatipoglu, N Arda… - Bioorganic & Medicinal …, 2017 - Elsevier
Palladium complexes are potent and less toxic molecules in … two palladium(II) saccharinate
complexes with terpyridine for … to determine if two Pd(II) complexes of terpyridine were also …

Addition of niclosamide to palladium (II) saccharinate complex of terpyridine results in enhanced cytotoxic activity inducing apoptosis on cancer stem cells of breast …

D Karakas, B Cevatemre, N Aztopal, F Ari… - Bioorganic & Medicinal …, 2015 - Elsevier
… that Pd(II) complexes had high cytotoxic activities against various tumor cell lines including
human cervical epithelioid carcinoma, humanApoptosis inducing effect of Pd(II) complex on …

A palladium (II)–saccharinate complex of terpyridine exerts higher anticancer potency and less toxicity than cisplatin in a mouse allograft model

Y Cetin, Z Adiguzel, HU Polat, T Akkoc, A Tas… - Anti-Cancer …, 2017 - journals.lww.com
palladium (II)(Pd)–saccharinate complex with terpyridine. To characterize the Pd (II) complex
… The antitumor efficacy and safety of the Pd (II) complex in-vivo were examined by analyzing …

Anticancer effect of a novel palladiumsaccharinate complex of terpyridine by inducing apoptosis on Ehrlich ascites carcinoma (EAC) in Balb-C mice

EI Ikitimur-Armutak, K Sonmez, K Akgun-Dar… - Anticancer …, 2015 - ar.iiarjournals.org
… In these preliminary studies, it was demonstrated that the anticancer activity against human
breast and lung cancer cells of certain complexes occurs by inducing apoptosis through cell …

… and cell death-inducing effect of novel palladium (II) and platinum (II) saccharinate complexes with 2-(hydroxymethyl) pyridine and 2-(2-hydroxyethyl) pyridine on …

F Ari, N Aztopal, C Icsel, VT Yilmaz, E Guney… - Bioorganic & medicinal …, 2013 - Elsevier
… ″-terpyridine (terpy) were found to be highly cytotoxic on a … of 1–4 on lung cancer (A549
and PC3), human hepatoma Hep3B … The apoptosis inducing effect of the complex 2 was …

DNA binding and cleavage studies of two palladium (II) saccharinate complexes with terpyridine

C Icsel, VT Yilmaz - DNA and Cell Biology, 2013 - liebertpub.com
effect of novel palladium(II) and platinum(II) complexes on non-… of a novel palladium(II)
complex on human breast cancer cells … of a novel palladium(II) complex on human breast cancer …

Apoptosis-inducing effect of a palladium (II) complex-[PdCl (terpy)](sac). 2H2O] on Ehrlich ascites carcinoma (EAC) in mice

EI Ikitimur-Armutak, E Ulukaya, E Gurel-Gurevin… - in vivo, 2016 - iv.iiarjournals.org
… , the effect of a Pd(II) complex (Pd(II)-saccharinate complex of terpyridine) on cell death, cell
proliferation and cell survival was investigated in vivo. Several Pd(II)-based complexes have …

Synthesis, structures and anticancer potentials of platinum (II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting …

VT Yilmaz, C Icsel, OR Turgut, M Aygun… - European journal of …, 2018 - Elsevier
… activity of the complexes was tested against human breast (… of [Pd 2 ((C,N)L) 2 (μ-sac) 2 ]
[44] (K b = 1.05 × 10 5 M −1 ) and [… undergo apoptotic cell death with the apoptosis inducing