Association of HLA-G polymorphisms with nasopharyngeal carcinoma risk and clinical outcome

N Ghandri, S Gabbouj, K Farhat, N Bouaouina… - Human immunology, 2011 - Elsevier
The expression of human leukocyte antigen–G (HLA-G) in tumor cells may facilitate the
escape of the tumor from immunosurveillance; thus the aim of this study was to evaluate the
influence of HLA-G polymorphisms occurrence on nasopharyngeal carcinoma (NPC)
susceptibility, severity, and survival. Using the restriction fragment length polymorphism–
polymerase chain reaction and the amplification refractory mutation system–polymerase
chain reaction method, 186 Tunisian patients and 189 healthy controls were genotyped for …
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