Association of KCNJ11 (RS5219) gene polymorphism with biochemical markers of glycemic status and insulin resistance in gestational diabetes mellitus

M Lenin, R Ramasamy, S Kulkarani, S Ghose… - Meta Gene, 2018 - Elsevier
Background In gestational diabetes mellitus, pregnancy induced insulin resistance (IR) is
counterbalanced by an increase in beta-cell mass and subsequent increase in insulin
secretion for which the genetic makeup of an individual plays an important role. Our study
aimed to explore the association between the SNP of KCNJ11 (rs5219) gene and
biochemical markers of glycemic status and IR in GDM. Methodology 240 pregnant women
without GDM and 230 with GDM were selected for study based on DIPSI (The Diabetes In …
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