Association of mannose-binding lectin gene (MBL2) polymorphisms with rheumatoid arthritis in an Indian cohort of case-control samples
Single nucleotide polymorphisms in the mannose-binding lectin (MBL2) gene, as well as the
serum MBL2 level, have been associated with various autoimmune diseases. We
investigated whether such polymorphisms and/or the serum MBL2 level were associated
with rheumatoid arthritis (RA) in an Indian population. The frequency of the B variant (codon
54) of the MBL2 gene was quite frequent in the healthy Indian population and was
significantly (P= 6.35× 10− 6) lower in RA patients. We replicated this association (P= 1.78× …
serum MBL2 level, have been associated with various autoimmune diseases. We
investigated whether such polymorphisms and/or the serum MBL2 level were associated
with rheumatoid arthritis (RA) in an Indian population. The frequency of the B variant (codon
54) of the MBL2 gene was quite frequent in the healthy Indian population and was
significantly (P= 6.35× 10− 6) lower in RA patients. We replicated this association (P= 1.78× …
Association of mannose-binding lectin gene (MBL2) polymorphisms with rheumatoid arthritis in an Indian cohort of case-control samples.
BG Bhawna Gupta, CA Charu Agrawal, SK Raghav… - 2005 - cabidigitallibrary.org
Single nucleotide polymorphisms in the mannose-binding lectin (MBL2) gene, as well as the
serum MBL2 level, have been associated with various autoimmune diseases. We
investigated whether such polymorphisms and/or the serum MBL2 level were associated
with rheumatoid arthritis (RA) in an Indian population. The frequency of the B variant (codon
54) of the MBL2 gene was quite frequent in the healthy Indian population and was
significantly (P= 6.35× 10-6) lower in RA patients. We replicated this association (P= 1.78× …
serum MBL2 level, have been associated with various autoimmune diseases. We
investigated whether such polymorphisms and/or the serum MBL2 level were associated
with rheumatoid arthritis (RA) in an Indian population. The frequency of the B variant (codon
54) of the MBL2 gene was quite frequent in the healthy Indian population and was
significantly (P= 6.35× 10-6) lower in RA patients. We replicated this association (P= 1.78× …
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