… with cellular changes that precede the progression to atrophy. Because we hypothesized
that pegcetacoplan would protect unaffected regions of the retina, we chose to exclude the …

… area of retinal pigment epithelium and outer retinal atrophy in … that encompasses both
incomplete RORA and complete … into the protective association of pegcetacoplan treatment …

… with cellular changes that precede the progression to atrophy. Because we hypothesized
that pegcetacoplan would protect unaffected regions of the retina, we chose to exclude the tran…

… –based segmentation of retinal pigment epithelium (RPE) … intravitreal pegcetacoplan showed
reduced GA progression … not only complete loss but also incomplete damage adds to the …

… beyond areas of retinal pigment epithelium atrophy is a … as a part of incomplete RPE and
outer retinal atrophy (iRORA) 57,… effect of pegcetacoplan on RPE-atrophy progression rates in …

… pegcetacoplan monthly, 205 pegcetacoplan every … pegcetacoplan monthly, 201 pegcetacoplan
every other month, and 195 sham). In OAKS, pegcetacoplan monthly and pegcetacoplan …

… is characterized by loss of retinal pigment epithelium, photoreceptors, and underlying …
contribute to development and progression of AMD remains incomplete. Given the potential …

… incomplete retinal pigment epithelium outer retinal atrophy (iRORA) and complete retinal
pigment epithelium outer retinal … pegcetacoplan may be beneficial in earlier stages of AMD [29]. …

… However, there was no association with disease progression once GA had already … of
pegcetacoplan on the progression of incomplete retinal pigment epithelium and outer retinal …

… The retinal pigment epithelium (RPE) and retinal ganglion … atrophy (cRORA) and incomplete
RORA (iRORA) based on OCT [… receiving pegcetacoplan to have lower rates of progression …