Association of red blood cell transfusion, anemia, and necrotizing enterocolitis in very low-birth-weight infants

RM Patel, A Knezevic, N Shenvi, M Hinkes, S Keene… - Jama, 2016 - jamanetwork.com
Importance Data regarding the contribution of red blood cell (RBC) transfusion and anemia
to necrotizing enterocolitis (NEC) are conflicting. These associations have not been
prospectively evaluated, accounting for repeated, time-varying exposures. Objective To
determine the relationship between RBC transfusion, severe anemia, and NEC. Design,
Setting, and Participants In a secondary, prospective, multicenter observational cohort study
from January 2010 to February 2014, very low-birth-weight (VLBW,≤ 1500 g) infants, within …
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