Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease subjects
Background Genetic analyses have identified many variants associated with the risk of
inflammatory bowel disease (IBD) development. Among these variants, the ones located
within the NOD2 gene have the highest odds ratio of all IBD genetic risk variants. Also,
patients with Crohn's disease (CD) have been shown to have an altered gut microbiome,
which might be a reflection of inflammation itself or an effect of other parameters that
contribute to the risk of the disease. Since NOD2 is an intracellular pattern recognition …
inflammatory bowel disease (IBD) development. Among these variants, the ones located
within the NOD2 gene have the highest odds ratio of all IBD genetic risk variants. Also,
patients with Crohn's disease (CD) have been shown to have an altered gut microbiome,
which might be a reflection of inflammation itself or an effect of other parameters that
contribute to the risk of the disease. Since NOD2 is an intracellular pattern recognition …
[PDF][PDF] Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease
Background: Genetic analyses have identified many variants associated with the risk of
inflammatory bowel disease (IBD) development. Among these variants, the ones located
within the NOD2 gene have the highest odds ratio of all IBD genetic risk variants. Also,
patients with Crohn's disease (CD) have been shown to have an altered gut microbiome,
which might be a reflection of inflammation itself or an effect of other parameters that
contribute to the risk of the disease. Since NOD2 is an intracellular pattern recognition …
inflammatory bowel disease (IBD) development. Among these variants, the ones located
within the NOD2 gene have the highest odds ratio of all IBD genetic risk variants. Also,
patients with Crohn's disease (CD) have been shown to have an altered gut microbiome,
which might be a reflection of inflammation itself or an effect of other parameters that
contribute to the risk of the disease. Since NOD2 is an intracellular pattern recognition …