Automated voxel-by-voxel tissue classification for hippocampal segmentation: methods and validation
The hippocampus is an important structural biomarker for Alzheimer's disease (AD) and has
a primary role in the pathogenesis of other neurological and psychiatric diseases. This study
presents a fully automated pattern recognition system for an accurate and reproducible
segmentation of the hippocampus in structural Magnetic Resonance Imaging (MRI). The
method was validated on a mixed cohort of 56 T1-weighted structural brain images, and
consists of three processing levels:(a) Linear registration: all brain images were registered to …
a primary role in the pathogenesis of other neurological and psychiatric diseases. This study
presents a fully automated pattern recognition system for an accurate and reproducible
segmentation of the hippocampus in structural Magnetic Resonance Imaging (MRI). The
method was validated on a mixed cohort of 56 T1-weighted structural brain images, and
consists of three processing levels:(a) Linear registration: all brain images were registered to …