Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration

P Grumati, L Coletto, P Sabatelli, M Cescon… - Nature medicine, 2010 - nature.com
Autophagy is crucial in the turnover of cell components, and clearance of damaged
organelles by the autophagic-lysosomal pathway is essential for tissue homeostasis.
Defects of this degradative system have a role in various diseases, but little is known about
autophagy in muscular dystrophies. We have previously found that muscular dystrophies
linked to collagen VI deficiency show dysfunctional mitochondria and spontaneous
apoptosis, leading to myofiber degeneration. Here we demonstrate that this persistence of …

[引用][C] Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration

이선진 - KSBMB News, 2012 - kiss.kstudy.com
Autophagy is defective in collagen VI muscular dystrophies,, and its reactivation rescues
myofiber degeneration - KSBMB News - 생화학분자생물학회 - KISS 34.64.82.79 회원가입
로그인 고객센터 한국어 ENG 지식을 담다. 지식을 나누다 KISS 상세검색 34.64.82.79 한국어
ENG 로그인 회원가입 close menu 고객센터 생화학분자생물학회 KSBMB News Autophagy is
defective in collagen VI muscular dystrophies,, and its reactivation rescues myofiber
degeneration Autophagy is defective in collagen VI muscular dystrophies,, and its …
以上显示的是最相近的搜索结果。 查看全部搜索结果