… , only few founder mutations have been described. We screened 453 Chilean patients with
hereditary breast cancer for mutations in BRCA1 and BRCA2. For recurrent mutations, we …

… proportions of BRCA1 and BRCA2 mutation carriers are 3.1% and 3.0… UK, BRCA2 mutations
are likely to account for more cases of … Germline mutations of the BRCA1 gene in breast and …

… of mutations in the BRCA1 and BRCA2 genes among … , 2 large founder deletions in the
BRCA1 gene accounted for … reporting that BRCA carriers affected with early-onset breast cancer …

… of inherited risk of breast and ovarian cancer (hereditary breast … , 32 to 78 years) for
BRCA1-mutation carriers and 55 years (… Nonfounder mutations accounted for 16 (21.6%) of the 74 …

… , the mutation rate of BRCA1/2 genes was 23.0% in 78 familial … Germline mutations in BRCA1
and BRCA2 genes account … between BRCA1 and BRCA2 carriers was observed, BRCA1 …

… Mutations in the BRCA1 and BRCA2 genes account for the … rearrangements in BRCA1 and
BRCA2 and germline mutations of … 78% to 96% of Ashkenazi Jews with detectable mutations …

… Breast cancer is rare in men and accounts for less than 1% of all … lifetime risk of male breast
cancer in BRCA2 mutation carriers is … Among women, mutations in the BRCA1 gene seem to …

… Germline mutations in breast cancer 1 gene (BRCA1) and … confidence interval [CI]: 44–78%)
and for ovarian cancer was … that a BRCA1 or BRCA2 gene mutation accounts for the pattern …

… identify some BRCA1 and BRCA2 mutation carriers among the … for the three Ashkenazi
founder mutations and a duplication in … to detect coding region mutations in BRCA1 and 72 were …

… the search for the BRCA1 and BRCA2 genes and, therefore, by … risk of breast cancer among
carriers of a BRCA1 mutation, … purpose of finding the two genes been estimated to be lower […