Background. BCC is currently the most common type of skin cancer in humans. Although
having a low‐grade malignancy and metastatic potential, BCC is locally aggressive and
destructive. Despite numerous studies, the origin of BCC, whether arising from the follicular
or interfollicular layer, remains controversial. Objectives. This study aims to evaluate whether
BCC arises from the follicular or interfollicular layer by using immunohistochemical staining.
Methods. Twenty‐three specimens of superficial and nodular BCC at its very early stage …